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X chromsome inactivation


Bio-Hazard

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I've been trying to understand X inactivation; I haven't been able to figure it out.

 

From what I think I understand, X inactivation has to do with repressing an allele that gives out a certain phenotype.

 

What I don't understand is how calico cats have different colors of fur.

I was reading part of wikipedia and I'm assuming this explains why both genes are expressed in calico cats.

 

Expressed genes on the inactive X chromosome

- http://en.wikipedia.org/wiki/X-inactivation

 

During cell differentiation, some cells activate the allele that was packed away?

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I've been trying to understand X inactivation; I haven't been able to figure it out.

 

From what I think I understand, X inactivation has to do with repressing an allele that gives out a certain phenotype.

 

What I don't understand is how calico cats have different colors of fur.

I was reading part of wikipedia and I'm assuming this explains why both genes are expressed in calico cats.

 

Expressed genes on the inactive X chromosome

- http://en.wikipedia.org/wiki/X-inactivation

 

During cell differentiation, some cells activate the allele that was packed away?

 

good question!!!! I am not sure! I always thought the reason calico cats were different colours was because of recessive genes, or becuase of incomplete dominace and codominace. I never considered X-inactivation!!!! Looks like I got some research to do! =)

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