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Borna Virus in psychiatric patients


Michaelangelica

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  • 4 months later...

I have just now read that two substances inhibit Borna Virus. These are currently in the research stage, and go by the chemical names of: 1-beta-d-Arabinofuranosylcytosine and 2'-Fluoro-2'-Deoxycytidine. They both inhibit Borna Disease Virus replication and spread. You can find the published research studies just by searching in Google with the terms:

 

Arabinofuranosylcytosine + Borna, and: Deoxycytidine + Borna

 

Hopefully, these two drugs will be available soon.

 

Anyone know anything about these chemicals?

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Well, it appears that 1-beta-d-Arabinofuranosylcytosine inhibits DNA polymerase and produces S phase–specific cytotoxicity.

 

2'-Fluoro-2'-Deoxycytidine also inhibits RNA and protein levels. This chemical isn't as cytotoxic as Arabinofuranosylcytosine, and has also been used for HIV and Herpes.

 

http://aac.asm.org/cgi/reprint/48/4/1422.pdf

CYTARABINE (1-BETA-D-ARABINOFURANOSYLCYTOSINE)

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  • 2 years later...

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