davekm Posted February 11, 2013 Report Share Posted February 11, 2013 Caffeine increases BDNF, and prevents stress induced decreases in BDNF. However, chronic BDNF downregulates the TrkB receptor. - http://www.ncbi.nlm.nih.gov/pubmed/8752592 This is true of caffeine as well. -http://www.ncbi.nlm.nih.gov/pubmed/22841916 Does downregulation of TrkB stops BDNF from performing it's functions, like neuroprotection and neurogenesis? Quote Link to comment Share on other sites More sharing options...
davekm Posted February 20, 2013 Author Report Share Posted February 20, 2013 (edited) duplicate post Edited February 20, 2013 by davekm Quote Link to comment Share on other sites More sharing options...
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