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Cytotoxic Cellular Pastes


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#1 VictorMedvil

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Posted 30 December 2018 - 07:59 AM

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Extremophile [Bacteria/Fungus/Plant/Viruses]  (45,5') , I consider to be much more powerful than the Standard Hostile Multivalent Metamorphic Virus, but would take time to kill an entire phylum on a planet around 1 to 2 years just as a Multivalent Metamorphic Virus takes about that much time to kill a continent.  This below one infects Bacteria being the ultimate Bacteria killer giving immunity to bacteria to cellular targets such as white blood cells.

 

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I theorize such devices would extinct entire phylum such as Fish, Birds, or Mammals (https://en.wikipedia...xtinction_event) on a planetary scale, which are Type III Genetic Warfare Devices "Type II Harvesters" or Type II Metamorphic Weapons.

https://en.wiktionar...wiki/biomachine

 

More about the subject

 

https://cen.acs.org/...elopment/96/i26

 

https://en.wikipedia...thnic_bioweapon

 

 

 

 Type I "Harvesters" = http://civilization....ineering_(SMAC)

 

Type II "Harvesters" = http://civilization....achinery_(SMAC)

 

 

 

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5/21/2018


Edited by VictorMedvil, 10 April 2019 - 03:00 AM.


#2 exchemist

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Posted 31 December 2018 - 04:47 PM

2ilea6u.png

 

Extremophile [Bacteria/Fungus/Plant/Viruses]  (45,5') , I consider to be much more powerful than the Standard Hostile Multivalent Metamorphic Virus, but would take time to kill an entire phylum on a planet around 1 to 2 years just as a Multivalent Metamorphic Virus takes about that much time to kill a continent. 

 

21dd0a001ebce907ca125fe03cd076ea.png

 

 

I theorize such devices would extinct entire phylum such as Fish, Birds, or Mammals (https://en.wikipedia...xtinction_event) on a planetary scale, which are Type III Genetic Warfare Devices "Type II Harvesters" or Type II Metamorphic Weapons.

https://en.wiktionar...wiki/biomachine

 

More about the subject

 

https://cen.acs.org/...elopment/96/i26

 

https://en.wikipedia...thnic_bioweapon

 

 

 

 Type I "Harvesters" = http://civilization....ineering_(SMAC)

 

Type II "Harvesters" = http://civilization....achinery_(SMAC)

 

 

 

2jfypfn.jpg

 

 

5/21/2018

Oh good I'm going to steal this idea and patent it........just as I did with all your other ideas.  :winknudge:

 

But I thought you had left.........????


Edited by exchemist, 31 December 2018 - 04:48 PM.


#3 VictorMedvil

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Posted 23 February 2019 - 08:38 PM

Early experiments in Cytotoxic Metamorphic Cellular Pastes have shown the extreme ability to exchange genetic material via Horizontal gene transfer actually making them extremely infectious able to transfer genetic material via two methods of gene transfer that being plasmid exchange and Viral Transfection while also having the ability to reproduce  being a Hybrid Bacteria/Fungus/Plant/Virus much like the Harmless Metamorphic Gel types being actually a more highly genetically engineered form of the Metamorphic Gel type 1 with other Genes that make it much more resistant and invasive with Multivalent Harmful self replicating Viruses that reproduce the C.M.C.P. by being a Lysogenic cycle Transfer Vector added being a True Ethnic Bio-weapon being extinction level pathogen which does ecophagy the target object by three ways of reproduction Plasmid Transformation,Viral Transfection and Cellular Division.

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Edited by VictorMedvil, 24 February 2019 - 09:27 AM.


#4 VictorMedvil

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Posted 26 February 2019 - 05:56 PM

In any case, For the Metamorphic Cytotoxic Cellular Paste to function we must have a gene sequence for the Cellular part of it that is less than 180,000 bp to be delivered via Viral Transfection which leaves ruffly after the Virus genes are put into the device around 54 genes for the plasmid exchange and reproduction genes along with the neurotoxin or necrosis causing poisonous genes. I will begin to gene tailor the device like the Nano-fabricated Gene therapy vectors to make the most efficient and dangerous code to make a Type II Genetic Weapon able to reproduce in 3 ways, the first genes being a lethal self replicating retroviral/Phage device being at the beginning of the Code with LTR5' and ending it with LTR3'. This being able to infect Bacteria and Animal Cells with the Metamorphic Paste Transformation Genes which uses a Total of 6 genes assuming each gene is around 3000 bp which some are smaller but on average genes are around 3000 bp.

 

Omni Targetting Viral Transmission

 

LTR5' -  Pol - 54 Metamorphic Cellular Genes- Chicken Pox Caspid - ENV HIV-1 - VSV-G - Bacteria Phage Structure Genes -LTR3'

 

Which is basically a Extended Retroviral Vector along with Bacteriophage including the Metamorphic Genes for the Viral Insertion of the Genes that make the Metamorphic Paste transmit to other cells via a viral route which encodes the entire genome of the C.M.C.P. into harmless bacteria making them C.M.C.P by Viral Transmission of genes into the organism causing a Metamorphic Effect into more C.M.C.P. Cells with the same ability.

 

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Edited by VictorMedvil, 26 February 2019 - 08:01 PM.


#5 VictorMedvil

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Posted 28 February 2019 - 08:05 PM

A set of stronger promoters needs to be added into front of the Pol gene for multiple replications of integrase and reverse transcriptase proteins for both the Bacteriophage and Retroviral Transmission of the Metamorphic Paste as the Machinery of Pol is used in both versions of the viral transmission of the organism, a stronger promoter than the standard is needed for two Viral Vector-like transmissions rather than the standard single virus envelope since there are two separate viral buds.

 

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Edited by VictorMedvil, 28 February 2019 - 08:10 PM.


#6 VictorMedvil

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Posted 10 April 2019 - 02:21 AM

Taking from Craig Venter's work on the synthetic bacterial genome, we next create the "Black" section of the Cytotoxic Cellular Paste's Genome being the body to be transferred, The Addition of these genes to any cell or bacteria should transform the bacteria or cell into a Cytotoxic Cellular Paste with the same genetic enhancements and functions as the parent Cytotoxic Cellular Paste giving it its metamorphic pathogen status as the genetic changes metamorph the subject cell or bacteria with highly expressed genes. Upon insertion the function of the cell or bacteria should be rooted turned into a "Zombie" form of the original being controlled by the new gene insertions, Thus the Metamorphic Gene Cassette must take over dominance of the cellular or bacterial construct, then be able to reproduce in the same manner as the original using the Viral Horizontal Gene transfer methods being inserted too, we have 100,000 bp to work with which is the max size of genetic material the Backbone Viral parts of the Cytotoxic Cellular Paste can transfer, it is much like when a Worm takes over a computer, malicious code or in this case genes must be inserted to overthrow the host machine turning the Host Machine into a infectious Cytotoxic Cellular Paste.

 

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Every-time a new species of Cell or Bacteria is infected by the Progenitor Cytotoxic Cellular Paste's and new Variant of the original is created by recombination of the original's genes with the new host which the inserted Gene Cassette should be able to control or change the function of the construct, while the original genome of the transformed cell or bacteria will control cellular division and basic cellular metabolic function. The plasmid exchange part of the horizontal gene transfer will only be functional in bacterial targets which will also transfer the new genetic material to other types of bacteria, though via Viral Transmission Bacterial targets can still be initially infected using the Bacteriophage Transfer route.


Edited by VictorMedvil, 10 April 2019 - 02:54 AM.


#7 VictorMedvil

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Posted 16 June 2019 - 01:50 PM

Now for a sample gene cassette, let's say that you wanted to ability to genetically engineer any cell infected on the fly, you could insert the protein CRISPR which is way under the 33 gene limit of these devices being a single gene. You would insert CRISPR within the LTR5' and LTR3' this would allow any bacteria or cell infected to be genetically engineered just like in retroviral Vectors when CRISPR is inserted as the transfer gene, The Metamorphic Paste in this form would not be hostile just a gene storage and transfer device much like a plasmid but with more storage capacity that has multiple routes of transfer

 

Example Retroviral Plasmid with CRISPR Inserted.

Cellecta-p-RSGCCP-U6-sg-HTS6-C-CMV-Cas9-

 

Though the Metamorphic Plasmid would contain up to 32 more Large Genes besides CRISPR transferring the Genes into Bacteria and Animal cells in this example device breaking the limitations of standard retroviral Plasmids using Hybridized Viral Vectors to transfer the genes in question because of the changed caspid proteins lacking the small carrying capacity of HIV-1 ENV instead using the larger Chickenpox Caspid and Bacteriophage Shell, Where as the Retroviral Plasmid Above is near filling the carrying capicity of the vector, these metamorphic vectors are not near their carrying capacity of 100,000 bp carrying the genetic material of this vector being at around 3.5% of max carrying the CRISPR above versus the Retroviral Vector is at 37.5% of max. This shows the amount of data transfer that can be transferred by these Metamorphic Vectors nearly 11 times the genetic data showing the superiority of Hybrid Vectors giving plenty of room for Malicious or Therapeutic genes that is one of the reasons it is a Type II Device and not a Type I like this Standard Retroviral Vector above.

 

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Edited by VictorMedvil, 16 June 2019 - 02:48 PM.