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Zebrafish As A Model Organism

zebrafish development toxicity

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#1 nmda1



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Posted 06 September 2018 - 09:25 AM

I have been doing some research on zebrafish toxicity assay, and I have noticed that in many published articles zebrafish embryos are said to be exposed to different compounds at 6 hpf, not before that. Could anyone explain to me why the embryos aren't used in earlier stages of development, for example 4-5 hpf, does it have something to do with certain gene expression, and if so, which genes are included?
Thank you very much for your answers, anything will help.


Also tagged with one or more of these keywords: zebrafish, development, toxicity