Jump to content
Science Forums

norcioortiz

Recommended Posts

Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. They are found in multicellular organisms. In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. In a developing embryo, stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm (see induced pluripotent stem cells)—but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues. - (Wikipedia and Google.com)

 

 

 

Fetal Stem Cells Can Repair the Mother During Pregnancy

[sPAMlink removed]

One of the benefits of pregnancy is increased regenerative ability in the mother, a fact observed in a number of studies. The underlying mechanisms are illustrated in recent research, and is one of [sPAMlink removed] that might inform future research directions in regenerative medicine: "Scientists are devoting countless research hours to treatments based on embryonic stem cells, differentiatingthese blank-slate cells from embryos into brain cells, light-sensing retinal cells, blood cells, and more to replace damaged or destroyed tissues in the body. Now, a new study in mice shows such that nature has arrived at just such a solution, too: When a pregnant mouse has a heart attack, her fetus donates some of its stem cells to help rebuild the damaged heart tissue. ... The researchers started with two lines of mice: normal mice and mice genetically engineered to express green fluorescent protein (GFP), which glows a distinctive green when exposed to blue light, in their cells. They mated normal female mice with GFP-producing male mice. This meant that half the resulting fetuses had the GFP gene, too, making their cells glow, too. Twelve days later - a little less than two-thirds of the way through a normal mouse pregnancy - the researchers gave half the pregnant mice heart attacks. When the scientists examined the female mice's heart tissue two weeks after the heart attacks, they found lots of glowing green tissue - cells that came from the fetus - in the mom's heart. Mice who had heart attacks had eight times as many cells from the fetus in their hearts as mice who hadn't had a heart attack did, meaning the high volume of fetal cells was a response to the heart attack. ... Doctors have observed that women who experience weakness of the heart during pregnancy or shortly after giving birth have better recovery rates than any other group of heart failure patients. This study suggests that fetal stem cells may help human mothers, as well as mice, recover from heart damage."

Link: http://blogs.discovermagazine.com/80beats/2011/11/21/helpful-mouse-fetuses-naturally-send-stem-cells-to-mom-to-fix-her-damaged-heart/

 

 

Comments

Edited by CraigD
SPAMlinks removed
Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
×
×
  • Create New...